Pilot radiogenomic evaluation of colorectal cancer - Are there preoperative radiological features of the dMMR phenotype?
- Resource Type
- Article
- Authors
- Lloyd, Angus J.; Ryan, Éanna J.; Clifford, Simon M.; MacDermott, Roisin; Stakelum, Áine; Climent, Marta; Sheahan, Kieran; Kennelly, Rory; Hanly, Ann; Martin, Sean T.; Winter, Desmond C.; Skehan, Stephen J.
- Source
- The Royal College of Radiologists Open; January 2023, Vol. 1 Issue: 1
- Subject
- Language
- ISSN
- 27730662
Microsatellite instability (MSI) is reflective of a deficient mismatch repair system (dMMR) and occurs in approximately 15–20% of all colorectal cancers (CRC). MMR status is increasingly tested due to its prognostic and predictive significance in CRC.