The article presents a study on the occurrence of Salmonella species (spp.) and Escherichia (E.) coli in the feces samples of sparrows. The study also seeks to determine the pathogenicity, cytotoxicity and sensitivity profile of the isolates to antimicrobial use. It notes that E. coli infections in the industrial poultry breeding sector leads to a diversity of diseases and severe economic losses while Salmonella infections can cause acute and/or chronic diseases to affected animals. Samples from 228 sparrows have been examined, 30 of which tested positive for E. coli infection, five were resistant to antibiotics and one was positive for Salmonella infection.