Does postoperative inflammation or sepsis generate neutrophil extracellular traps that influence colorectal cancer progression? A systematic review
- Resource Type
- Article
- Authors
- Carroll, Georgia M.; Burns, Grace L.; Petit, Joel A.; Walker, Marjorie M.; Mathe, Andrea; Smith, Stephen R.; Keely, Simon; Pockney, Peter G.
- Source
- Surgery Open Science; April 2020, Vol. 2 Issue: 2 p57-69, 13p
- Subject
- Language
- ISSN
- 25898450
Colorectal cancer is the third most common cancer worldwide. Almost half of those that have a potentially curative resection go on to develop metastatic disease. A recognized risk for recurrence is perioperative systemic inflammation and sepsis. Neutrophil extracellular traps have been implicated as promotors of tumor progression. We aimed to examine the evidence in the literature for an association between neutrophil extracellular traps and postoperative metastasis in colorectal cancer.