Methods of estimating vancomycin use in an inpatient setting: days of therapy versus therapeutic drug monitoring–based exposure days
- Resource Type
- Article
- Authors
- Murakami, Shutaro; Hiroi, Junko; Tokuda, Yasuharu; Casabar, Ed; Honda, Hitoshi
- Source
- Infection Control & Hospital Epidemiology; March 2019, Vol. 40 Issue: 3 p375-379, 5p
- Subject
- Language
- ISSN
- 0899823X; 15596834
AbstractUnderestimating antimicrobial use based on days of therapy (DOT) is recognized for certain antimicrobial agents. We investigated the difference between DOT and therapeutic drug monitoring (TDM)–based exposure days in estimating vancomycin use and demonstrated that DOT may underestimate vancomycin exposure by ∼10%.