Bi-2212 (Bi2Sr2CaCu2O8+x) multifilamentary round wires possess manifold superior superconducting properties compared to other high temperature superconductors suitable for very high field magnet applications; however, vortex pinning investigation has so far been absent, principally due to the complicated wire microstructures. Taking advantages of the simpler film-like microstructure of Bi-2212 tapes, we studied the flux pinning dependence as a function of Sr content, and correlated the tape performance to that of wires. We observed that, with increasing Sr content from 1.34 to 2.13, critical temperature Tc, and Kramer field Hk at 20 K increase respectively, from 70.5 to 80.4 K, and from 3.5 to 6.7 T, whereas α, which is the power law dependence of critical current density Jc at 4.2 K (Jc∝H-α), decreases from 0.4 to 0.3. Our work shows that flux pinning in Bi-2212 wires can be further improved by optimizing the Sr content, and flux pinning on Bi-2212 tape is a versatile tool not only for wire pinning study but also for powder quality assurance.