Biomarkers for Systemic Therapy in Metastatic Breast Cancer: ASCO Guideline Update Q and A.
- Resource Type
- Article
- Authors
- Clark, Amy S.; Cobain, Erin F.; Dayao, Zoneddy; Somerfield, Mark R.; DeMichele, Angela; Henry, N. Lynn
- Source
- JCO Oncology Practice; Dec2022, Vol. 18 Issue 12, p830-833, 4p
- Subject
- THERAPEUTIC use of antineoplastic agents
GENETIC mutation
BIOPSY
PHOSPHOTRANSFERASES
PHYSICIAN-patient relations
METASTASIS
COMMUNICATION
TUMOR markers
BREAST tumors
- Language
- ISSN
- 26881527
The article reports that the ASCO published an update of its biomarkers for systemic therapy in metastatic breast cancer guideline. Topics include examines the guideline update revisited recommendations from the 2015 guideline and expanded the scope of the guideline to address testing for PIK3CA and ESR1 somatic variants and germline BRCA1, BRCA2, and PALB2 pathogenic variants to guide therapy.