The article presents a case study of a 50-year-old woman with a history of fibrotic interstitial lung disease and pulmonary hypertension who underwent bilateral lung transplantation because of progressive respiratory failure. Bronchoscopy revealed complete dehiscence of the right mainstem anastomosis. After the healing of the dehiscence, the patient's right lower lobe pneumonia has resolved, she has been liberated from mechanical ventilation, and her tracheostomy has been decannulated.