[Effect of 99m Tc elution in vivo from red cells on red cell volumes measured using autologous 99m Tc-labeled red cells: comparison with 51 Cr method].
- Resource Type
- Academic Journal
- Authors
- Gallet M; Unité de radiopharmacie, Centre Georges François Leclerc, Dijon, France.; Drouet C; Service de médecine nucléaire, Centre Georges François Leclerc, Dijon, France.; Girodon F; Service d'hématologie biologique, pôle biologie, CHU Dijon, France, Inserm U 1231, Université de Bourgogne, Dijon, France.; Nicolas A; Unité de radiopharmacie, Centre Georges François Leclerc, Dijon, France.; Riedinger JM; Unité de radiopharmacie, Centre Georges François Leclerc, Dijon, France, Département de biologie et de pathologie des tumeurs, Unité de biologie clinique, Centre Georges François Leclerc, Dijon, France.
- Source
- Publisher: John Libbey Eurotext Country of Publication: France NLM ID: 2984690R Publication Model: Print Cited Medium: Internet ISSN: 1950-6112 (Electronic) Linking ISSN: 00033898 NLM ISO Abbreviation: Ann Biol Clin (Paris) Subsets: MEDLINE
- Subject
- Language
- French
The purpose of this work was to compare the measured red-cell volume (RCV) using sodium pertechnétate [RCV- 99m Tc] compared to the reference technique using sodium radiochromate [RCV- 51 Cr] and to assess the influence of technetium-99 elution on the RCV- 99m Tc value. Ten patients had simultaneous measurements of RCV- 99m Tc and RCV- 51 Cr. Elution of Tc-99m from red blood cells was 2.9% and led to an average overestimation of RCV- 99m Tc of 3.7%. The introduction of individual tracer elution rates in the RCV- 99m Tc calculation corrects this overestimation.