Glycated haemoglobin or mean blood glucose as indicators of metabolic control in Type 2 diabetes?
- Resource Type
- Academic Journal
- Authors
- Pupillo M; Metabolism and Diabetes Unit, Ospedale Renzetti, Lanciano, Italy.; De Berardis G; Antenucci D; Minnucci A; Nicolucci A
- Source
- Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8508335 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8227 (Electronic) Linking ISSN: 01688227 NLM ISO Abbreviation: Diabetes Res Clin Pract Subsets: MEDLINE
- Subject
- Language
- English
The aim of the study was to assess whether HbA(1c) levels reflected mean blood glucose (MBG) levels in Type 2 diabetes. Despite the good correlation between HbA(1c) and MBG, one-third of the patients had consistently higher HbA(1c) or lower HbA(1c) levels than that expected under the hypothesis that HbA(1c) is solely determined by MBG, suggesting the existence of different haemoglobin glycation phenotypes. The use of HbA(1c) alone for glycemic control monitoring in these patients could be insufficient to clearly trace their risk of complications.