The role of large cavity sinus surgery in the management of chronic rhinosinusitis in non-steroidal anti-inflammatory drug exacerbated respiratory disease: a single-centre experience and long-term outcomes.
- Resource Type
- Academic Journal
- Authors
- Pendolino AL; Department of ENT, Royal National ENT & Eastman Dental Hospitals, London, United Kingdom.; Ear Institute, University College London, United Kingdom.; Bandino F; Department of ENT, Royal National ENT & Eastman Dental Hospitals, London, United Kingdom.; Navaratnam A; Department of ENT, Royal National ENT & Eastman Dental Hospitals, London, United Kingdom.; Ross T; Department of ENT, Royal National ENT & Eastman Dental Hospitals, London, United Kingdom.; Qureishi A; ENT Department, Oxford University Hospital, United Kingdom.; Randhawa P; Department of ENT, Royal National ENT & Eastman Dental Hospitals, London, United Kingdom.; Andrews P; Department of ENT, Royal National ENT & Eastman Dental Hospitals, London, United Kingdom.; Ear Institute, University College London, United Kingdom.
- Source
- Publisher: Cambridge University Press Country of Publication: England NLM ID: 8706896 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-5460 (Electronic) Linking ISSN: 00222151 NLM ISO Abbreviation: J Laryngol Otol Subsets: MEDLINE
- Subject
- Language
- English
Objective: This study aimed to discuss the role of large cavity functional endoscopic sinus surgery in the management of chronic rhinosinusitis with nasal polyps in patients with non-steroidal anti-inflammatory drug exacerbated respiratory disease.
Methods: This was a retrospective review of patients undergoing large cavity functional endoscopic sinus surgery for non-steroidal anti-inflammatory drug exacerbated respiratory disease from January 2016 to March 2022. Population characteristics, pre- and post-operative number of functional endoscopic sinus surgical procedures, endoscopic polyp grade, Lund-Mackay score and nasal symptoms were recorded.
Results: Thirteen consecutive patients with a median age of 47 years were included. They all failed maximal medical treatment and/or conservative functional endoscopic sinus surgery and underwent large cavity sinus surgery followed by post-operative maximal medical therapy. All patients showed an improvement in nasal symptoms with improved Lund-Mackay scores post-operatively. The median length of follow up was 1.5 years.
Conclusion: Large cavity functional endoscopic sinus surgery seems to halt the progression of chronic rhinosinusitis with nasal polyps in non-steroidal anti-inflammatory drug exacerbated respiratory disease. In this case series, large cavity functional endoscopic sinus surgery combined with optimal post-operative medical treatment appeared to switch off chronic rhinosinusitis with nasal polyps in patients with non-steroidal anti-inflammatory drug exacerbated respiratory disease.