Competing Interests: Competing interests: AH has served on scientific advisory boards for Galapagos, Novartis and Merck Serono; received speaker honoraria from Biogen Idec, Merck Serono and Novartis; and received limited research grants from Merck Serono. DB is an employee and shareholder of Kyverna Therapeutics. EF has received speaker honoraria from AbbVie, BMS, Galapagos, Janssen, Lilly, Novartis, Roche, Sanofi and Pfizer. GS has received speaker honoraria from BMS, Cabaletta, Janssen, Kyverna, Miltenyi and Novartis. DM has received speaker honoraria and consulting fees from Abbvie, BMS, Beigene, Celgene, Galapagos, Gilead, Janssen, Miltenyi and Novartis.