A Case of a Granular Cell Tumor Arising in a Patient with Long-segment Barrett's Esophagus.
- Resource Type
- Academic Journal
- Authors
- Yamada S; Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Japan.; Katayama Y; Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Japan.; Endoscopy Center, Dokkyo Medical University Saitama Medical Center, Japan.; Fujimoto Y; Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Japan.; Kobori I; Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Japan.; Kusano Y; Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Japan.; Soga K; Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Japan.; Sato T; Department of Pathology, Dokkyo Medical University Saitama Medical Center, Japan.; Matsushima J; Department of Pathology, Dokkyo Medical University Saitama Medical Center, Japan.; Ban S; Department of Pathology, Dokkyo Medical University Saitama Medical Center, Japan.; Tamano M; Department of Gastroenterology, Dokkyo Medical University Saitama Medical Center, Japan.
- Source
- Publisher: Japanese Society of Internal Medicine Country of Publication: Japan NLM ID: 9204241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7235 (Electronic) Linking ISSN: 09182918 NLM ISO Abbreviation: Intern Med Subsets: MEDLINE
- Subject
- Language
- English
Esophageal cell tumors are rare. Esophagogastroduodenoscopy performed on a 48-year-old woman revealed an elevated esophageal lesion and the presence of long-segment Barrett's esophagus. Endoscopic ultrasonography showed a 15 mm homogeneous hypoechoic tumor extending from the lamina propria mucosa to the submucosa. Pathological examination of the biopsy tissue revealed a sheet-like cluster of histiocytoid cells with an abundant eosinophilic granular cytoplasm. Immunohistochemical examination revealed S-100 (+) and CD68 (+), thus suggesting the diagnosis of a granular cell tumor. The tumor was resected by endoscopic submucosal dissection. Pathologically, the background mucosa was Barrett's mucosa. This is the first reported case of an esophageal granular cell tumor in long-segment Barrett's esophagus.