[Hormone anti-müllérienne (AMH) en pédiatrie : établissement de valeurs de référence avec le dosage de l'AMH Fujirebio ® Lumipulse G et comparaison avec le dosage Roche ® Elecsys sur les mêmes échantillons pédiatriques].
- Resource Type
- Academic Journal
- Authors
- Delaye JB; CHU Tours, In Vitro Nuclear Medecine Department, F-37044 Tours, France.; Le Tilly O; CHU Tours, Medical pharmacoly department, F-37044 Tours, France.; Enard E; CHU Tours, In Vitro Nuclear Medecine Department, F-37044 Tours, France.; Collet C; CHU Tours, In Vitro Nuclear Medecine Department, F-37044 Tours, France.; Emond P; CHU Tours, In Vitro Nuclear Medecine Department, F-37044 Tours, France, UMR 1253, iBrain, University of Tours, Inserm, 37000 Tours, France, University of Tours, PST Biological system assay, 37044 Tours Cedex 9, France.; Dufour-Rainfray D; CHU Tours, In Vitro Nuclear Medecine Department, F-37044 Tours, France, UMR 1253, iBrain, University of Tours, Inserm, 37000 Tours, France, Specialised biology group of the french Society of Nuclear Medicine, SFMN, 75270 Paris, France.
- Source
- Publisher: John Libbey Eurotext Country of Publication: France NLM ID: 2984690R Publication Model: Print Cited Medium: Internet ISSN: 1950-6112 (Electronic) Linking ISSN: 00033898 NLM ISO Abbreviation: Ann Biol Clin (Paris) Subsets: MEDLINE
- Subject
- Language
- French
We performed a method comparison between the Fujirebio® Lumipulse G AMH assay and the Roche® Elecsys AMH assay using the same pediatric samples. We described full pediatric gender and age-specific reference ranges for AMH using the Fujirebio® AMH assay on the Lumipulse G 600 II. The study was performed on 281 plasma samples collected in tubes with lithium heparin. The samples were from patients (135 males and 146 females) aged from 3 days to 22 years collected at the University Hospital Center of Tours. The Fujirebio® Lumipulse method showed excellent correlation with Roche® Elecsys but had a significant proportional positive bias. The data were used to propose pediatric reference values adapted to the Fujirebio® method. Our study described full pediatric gender and age-related reference ranges for AMH using the Fujirebio® AMH assay on the Lumipulse G600II. The delineation between normal male and female AMH concentrations make them valuable clinical tools for the monitoring of pediatric sexual and reproductive development from early childhood through the pubertal transition into adulthood.