Standard substances free quantification makes LC/ESI/MS non-targeted screening of pesticides in cereals comparable between labs.
- Resource Type
- Academic Journal
- Authors
- Wang T; National Food Institute, Research Group for Analytical Food Chemistry, Technical University of Denmark, Kemitorvet Building 202, Kgs. Lyngby, DK-2800, Denmark.; Liigand J; University of Tartu, Institute of Chemistry, Ravila 14a, Tartu 50411, Estonia.; Frandsen HL; National Food Institute, Research Group for Analytical Food Chemistry, Technical University of Denmark, Kemitorvet Building 202, Kgs. Lyngby, DK-2800, Denmark.; Smedsgaard J; National Food Institute, Research Group for Analytical Food Chemistry, Technical University of Denmark, Kemitorvet Building 202, Kgs. Lyngby, DK-2800, Denmark.; Kruve A; University of Tartu, Institute of Chemistry, Ravila 14a, Tartu 50411, Estonia; Department of Environmental Science and Analytical Chemistry, Stockholm University, Svante Arrhenius väg 16, 106 91 Stockholm, Sweden. Electronic address: anneli.kruve@su.se.
- Source
- Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
- Subject
- Language
- English
LC/ESI/MS is the technique of choice for qualitative and quantitative food monitoring; however, analysis of a large number of compounds is challenged by the availability of standard substances. The impediment of detection of food contaminants has been overcome by the suspect and non-targeted screening. Still, the results from one laboratory cannot be compared with the results of another laboratory as quantitative results are required for this purpose. Here we show that the results of the suspect and non-targeted screening for pesticides can be made quantitative with the aid of in silico predicted electrospray ionization efficiencies and this allows direct comparison of the results obtained in two different laboratories. For this purpose, six cereal matrices were spiked with 134 pesticides and analysed in two independent labs; a high correlation for the results with the R 2 of 0.85.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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