A severe pediatric life-threatening metabolic ketoacidosis.
- Resource Type
- Academic Journal
- Authors
- Roulland C; Pediatric Intensive Care Unit, CHU de Caen, F-14000 Caen, France.; Pediatric Emergency Unit, Centre Hospitalier de Luxembourg, L-1411 Luxembourg, Luxembourg.; Le Pallec C; Department of Pediatrics, CHU de Caen, F-14000 Caen, France.; Faucon C; Department of Pediatrics, CHU de Caen, F-14000 Caen, France.; Andre CO; Department of Pediatrics, CHU de Caen, F-14000 Caen, France.; Arion A; Department of Pediatrics, CHU de Caen, F-14000 Caen, France.; Goyer I; Department of Pharmacy, CHU de Caen, F-14000 Caen, France.; Brossier D; Pediatric Intensive Care Unit, CHU de Caen, F-14000 Caen, France.; Université Caen Normandie, medical school, F-14000 Caen, France.; METRICS, ULR2694, Université de Lille, F-59000 Lille, France.; CHU Sainte Justine Research Center, Université de Montreal, Montréal, Canada.
- Source
- Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101590741 Publication Model: eCollection Cited Medium: Print ISSN: 2251-6581 (Print) Linking ISSN: 22516581 NLM ISO Abbreviation: J Diabetes Metab Disord Subsets: PubMed not MEDLINE
- Subject
- Language
- English
- ISSN
- 2251-6581
This case report presents a 9-year-old child without underlying pathology, with a severe life-threatening non-diabetic metabolic ketoacidosis occurring less than 48 h after the onset of fasting and vomiting. The patient was admitted to the pediatric intensive care unit. He received volume expansion and maintenance fluid therapy which allowed a favorable evolution. Because of the unusual rapid onset of intense ketonemia and acidosis, a hereditary metabolic disease was investigated. The association between short fasting period and severe metabolic ketoacidosis has never been described in children outside of the neonatal period. This clinical case emphasizes urgent recognition, rigorous diagnostic and appropriate management in clinical practice.
Competing Interests: Conflict of interestAll authors have no conflicts of interest to disclose.
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