Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Outside this manuscript, Tine De Backer has served as a chairperson during a lecture for Bayer and Daiichi Sankyo and participated in an expert meeting for Pfizer. Outside this manuscript, Lies Lahousse has been consulted as expert for AstraZeneca. Outside this manuscript, Lies Lahousse has given a lecture sponsored by Chiesi, and Lies Lahousse and Maxim Grymonprez lectures sponsored by IPSA vzw, a non-profit organization facilitating lifelong learning for health care providers. Neither author has received any fees personally. All other authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.