Pharmacology For Age--Related Macular Degeneration.
- Resource Type
- Article
- Authors
- Singerman, Lawrence J.
- Source
- Review of Ophthalmology. Oct2004 Supplement 2, Vol. 11, p12-15. 4p.
- Subject
- *RETINAL degeneration treatment
*AGE factors in disease
*PHARMACOLOGY
*VASCULAR endothelial growth factors
*ADRENOCORTICAL hormones
*MONOCLONAL antibodies
*GENE therapy
- Language
- ISSN
- 1081-0226
Discusses developments in the pharmacology fore age-related macular degeneration. Macugen, an aptamer with a high affinity and high specificity for vascular endothelial growth factor (VEGF); Ranibizumab, a recombinant humanized anti-VEGF monoclonal antibody fragment; Corticosteroids; Anecortave acetate; Gene therapy; Squalamine;Illustration of extrafoveal, juxtafoveal and subfoveal choroidal neovascularization.