Peptide Rearrangement during Quadrupole Ion Trap Fragmentation: Added Complexity to MS/MS Spectra.
- Resource Type
- Article
- Authors
- Yagüe, Jesús; Paradela, Alberto; Ramos, Manuel; Ogueta, Samuel; Marina, Anabel; Barahona, Fernando; López de Castro, José A.; Vázquez, Jesús
- Source
- Analytical Chemistry. 3/15/2003, Vol. 75 Issue 6, p1524. 12p. 2 Diagrams, 17 Graphs.
- Subject
- *AMINO acids
*ION traps
*MASS spectrometry
- Language
- ISSN
- 0003-2700
Describes the presence of anomalous fragments, which correspond to neutral loss elimination of internal amino acids from ions of the b series in quadrupole ion trap mass spectroscopy (MS)/MS spectra from naturally occurring peptides. Preferential elimination of internal amino acid with aliphatic amino acids; Indication that some b ions underwent a structural rearrangement process.