Neuronal intranuclear inclusion disease (NIID) is the pathological hallmark of a heterogeneous neurodegenerative disease spanning dementia, neuropathy, parkinsonism, encephalitic episodes, and seizures.[1] Onset may be in infancy, childhood, or adulthood and be sporadic or familial. "Biopsy-positive" I NOTCH2NLC i -ET with normal imaging, however, may later progress to the characteristic DWI change of NIID.[10] I NOTCH2NLC- i NIID with typical imaging findings may present as stable adult-onset CD. NOTCH2NLC GGC Repeat Expansion Presenting as Adult-Onset Cervical Dystonia. [Extracted from the article]