Determination of the kinetic rate constant of cyclodextrin supramolecular systems by high performance affinity chromatography.
- Resource Type
- Article
- Authors
- Li, Haiyan; Ge, Jingwen; Guo, Tao; Yang, Shuo; He, Zhonggui; York, Peter; Sun, Lixin; Xu, Xu; Zhang, Jiwen
- Source
- Journal of Chromatography A. Aug2013, Vol. 1305, p139-148. 10p.
- Subject
- *CYCLODEXTRINS
*SUPRAMOLECULAR chemistry
*AFFINITY chromatography
*ACETAMINOPHEN
*SERTRALINE
*CAPILLARY electrophoresis
- Language
- ISSN
- 0021-9673
Highlights: [•] A modified HPAC method is proposed to determine k d of cyclodextrin supramolecules. [•] The plate height for the theoretical nonretained substance is estimated. [•] The k d for acetaminophen and sertraline are determined as 1.78 and 1.91s−1. [•] The k d value is consistent with that determined by capillary electrophoresis. [ABSTRACT FROM AUTHOR]