In this paper, the characteristics of flow-induced noise in ethylene cracking furnace tubes were analyzed, under both pre- and post-coking conditions, using the Large-Eddy Simulation (LES) and generalized Lighthill's acoustic analogy model. The results revealed that the flow-induced noise was broadband noise, with rapid attenuation occurring in the frequency range of 100–7800 Hz, and the primary energy concentrated between 25 and 500 Hz, in comparison to normal conditions. Acoustic sources coincide with areas of significant pulsations of static pressure and flow velocity, particularly above and behind the coke. Employing the Spearman correlation method for comparative analysis, it was observed that as the ratio of coke height to tube diameter (expressed as H/D) increased from 1/8 to 3/4, the proportion of static pressure pulsation decreased from 0.98 to 0.80, and the proportion of pulsating flow velocity decreased from 0.43 to 0.22. The data indicates a robust correlation between acoustic source and the static pressure pulsation. However, with the increase in coke, this correlation gradually diminishes, particularly concerning the pulsating flow velocity, where attenuation reached 48.83%. Additionally, the position and size of coke in the furnace tube can be determined using the Overall Sound Pressure Level (OASPL) curve measured in the tube. This OASPL curve exhibits distinct peaks, with corresponding OASPL values of 109 dBA, 120 dBA, 124 dBA, 131 dBA, and 149 dBA, respectively. The results presented in this paper offer essential insights for ensuring the safe operation of ethylene cracking furnace tubes. [ABSTRACT FROM AUTHOR]