Eye malformations associated with treatment with carbamazepine duringpregnancy.
- Resource Type
- Article
- Authors
- Sutcliffe, A.G.; Jones, R.B.; Woodruff, G.
- Source
- Ophthalmic Genetics. Jun98, Vol. 19 Issue 2, p59. 4p.
- Subject
- *CARBAMAZEPINE
*EYE abnormalities
*TERATOGENIC agents
*DRUG side effects
- Language
- ISSN
- 1381-6810
Four children are presented and their eye malformationsdescribed. One girl had bilateral anophthalmos, a boy and a girl had bilateralsevere microphthalmos, and a boy had a unilateral optic disc coloboma. Themothers of all four children were treated with carbamazepine during pregnancy.The teratogenic effect of carbamazepine and its likely role in the genesisof the eye malformations is discussed. [ABSTRACT FROM AUTHOR]