Hypoiodite-catalysed oxidative homocoupling of arenols and tandem oxidation/cross-coupling of hydroquinones with arenes.
- Resource Type
- Article
- Authors
- Uyanik, Muhammet; Nagata, Dai; Ishihara, Kazuaki
- Source
- Chemical Communications. 11/14/2021, Vol. 57 Issue 88, p11625-11628. 4p.
- Subject
- *OXIDATIVE coupling
*AROMATIC compounds
*BRONSTED acids
*HYDROGEN peroxide
*CATALYSIS
*OXIDIZING agents
- Language
- ISSN
- 1359-7345
We report the hypoiodite-catalyzed oxidative C–C homocoupling of arenols to biarenols or biquinones using aqueous hydrogen peroxide as an oxidant. In addition, by combining hypoiodite catalysis and lipophilic Lewis acid-assisted Brønsted acid catalysis under aqueous conditions, we achieved a tandem oxidation/cross-coupling reaction of hydroquinones with electron-rich arenes. These results highlight the substantial scope of hypoiodite/acid co-catalysis for use in oxidative coupling reactions. [ABSTRACT FROM AUTHOR]