A new paper-based biosensor for therapeutic drug monitoring.
- Resource Type
- Article
- Authors
- Lantigua, Darlin; Trimper, Jamie; Unal, Baris; Camci-Unal, Gulden
- Source
- Lab on a Chip. 9/7/2021, Vol. 21 Issue 17, p3289-3297. 9p.
- Subject
- *DRUG monitoring
*FLUIDIC devices
*DRUG utilization
*BIOSENSORS
*MICROFLUIDIC devices
*BLOOD volume
*MICROFLUIDICS
*TACROLIMUS
- Language
- ISSN
- 1473-0197
Tacrolimus is one of the most effective and prevalent drugs used to combat vascularized composite allotransplantation rejection. We have fabricated a rapid and easy-to-use six-layer paper based microfluidic device using the principles of competitive immunoassays and vertical flow microfluidics for colorimetric detection of tacrolimus in a small volume of blood. [ABSTRACT FROM AUTHOR]