Nicotine-like effects of cotinine on protein kinase C activity and noradrenaline release in bovine adrenal chromaffin cells.
- Resource Type
- Article
- Authors
- Vainio, P.J.; Viluksela, M.; Tuominen, R.K.
- Source
- Journal of Autonomic Pharmacology. Aug98, Vol. 18 Issue 4, p245. 6p.
- Subject
- *NICOTINE
*METABOLITES
*PROTEIN kinase C
*CHROMAFFIN cells
- Language
- ISSN
- 0144-1795
Studies the effect of cotinine, a metabolite of nicotine, on protein kinase C (PKC) distribution and nonadrenaline release in primary cultured bovine adrenal chromaffin cells. Changes in PKC activity; Role of cotinine in increasing phorbol binding to chromaffin cells.