Objective: The aim of the study was to evaluate the incidence and outcome of patients presenting with delirium during their ICU stay. Methods: Retrospective cohort study in ICU p. admitted from 1/7/15 to 30/11/17. Confussion Assesment Method for the Intensive care unit (CAM-ICU) was performed daily for delirium assessment. Two groups were analyzed: DP (with delirium) and DN (no delirium). Results: We included 2127 p. with 734 (34.5%) in DP group with a mean duration of 7.9±9 days while 1393 (65.5%) were in the DN group. Demographic data: age: DP 60.5±15.6, DN 56.7±16.5; APACHE II DP 17.2±7.7, DN 11.1±7; SAPS II DP 35.2±15.1, DN 23.4±14.3; ICU LOS DP median 11(5-20), DN 2(1-4); Mechanical Ventilation DP 507(69.1%), DN 221(15.9%); iv-sedation DP 456 (62.1%), DN 100(7.2%); iv-analgesia DP 489(66.6%), DN 283(20.3%); vasopressors DP 417(56.8%), DN 214(15.4%); transfusions CD 358(48.8%), DN 177(12.7%); infections DP 287(39.1%),DN 152(10.9%); ARF DP 184(25.1%), DN 115(8.2%), ICU mortality DP de 145(19.8%), DN 76(5.5%). The p was <0.05 for all the compared variables. Conclusion: Delirium was frequent in ICU patients showing a higher LOS, MV, vasopressors' and blood products', requirements, ARF, infections, and mortality rate compared to non-delirium patients. [ABSTRACT FROM AUTHOR]