Use of topical brimonidine to prevent intraocular pressure elevations following Nd: YAG-laser posterior capsulotomy.
- Resource Type
- Article
- Authors
- Singhal, Deepika; Desai, Roopali; Desai, Sejal; Shastri, Manisha; Saxena, Deepak
- Source
- Journal of Pharmacology & Pharmacotherapeutics. Apr2011, Vol. 2 Issue 2, p104-106. 3p. 3 Charts.
- Subject
- *PHARMACODYNAMICS
*INTRAOCULAR pressure
*TREATMENT of eye diseases
*DRUG efficacy
*ND-YAG lasers
*CATARACT
*EYE laser surgery
- Language
- ISSN
- 0976-500X
Objective: To study the effect of brimonidine on intraocular pressure (IOP) following capsulotomy among Indian subjects. Materials and Methods: The study was a nonrandomized trial with open label. Results: 80% of the subjects showed a decrease in IOP after instilling 0.2% brimonidine (1 hour pre capsulotomy). No such decrease was observed in control. After 1 and 4 h post capsulotomy a statistically signifi cant decrease in IOP ranging between 1-10 mmHg was found in 73.3% of the treatment group. Conclusions: In the present study 0.2% brimonidine has been proven effective to counteract the increase in IOP following Nd-YAG laser capsulotomy in Indian setting. [ABSTRACT FROM AUTHOR]