Microalgae are photosynthetic unicellular organisms that can be found in very different environments, both terrestrial and marine, including extreme environments such as cold, hot and high/low salinity [[1]]. They determined biomass and lipid algal content under different NaCl concentrations and studied the metabolic mechanism of lipid production of I C. sphacosum i GD under salt stress by using the transcriptome sequencing approach. Microalgae have attracted attention from researchers worldwide because they have been shown to be a valuable source of bioactive molecules and enzymes, with applications beneficial for human health and the environment (Figure 1). [Extracted from the article]