Time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of β cell function.
- Resource Type
- Article
- Authors
- Brown, Matthew R.; Sen, Satish K.; Mazzone, Amelia; Her, Tracy K.; Yuning Xiong; Jeong-Heon Lee; Javeed, Naureen; Colwell, Christopher S.; Rakshit, Kuntol; LeBrasseur, Nathan K.; Gaspar-Maia, Alexandre; Ordog, Tamas; Matveyenko, Aleksey V.
- Source
- Science Advances. 12/17/2021, Vol. 7 Issue 51, p1-19. 19p.
- Subject
- *SUPRACHIASMATIC nucleus
*PANCREATIC beta cells
*CELL physiology
*GENE enhancers
*PHYSIOLOGY
*MEDICAL sciences
*MOLECULAR biology
*HEAT shock proteins
- Language
- ISSN
- 2375-2548
The article presents a study that provides mechanistic insights into circadian regulation of beta cell function and corresponding beneficial effects of time-restricted feeding (tRF) in prevention of type 2 diabetes mellitus (T2DM). It mentions that how time-restricted feeding prevents deleterious metabolic effects of circadian disruption through epigenetic control of beta cell function.