Treatment of Pyonephritis Complicated by Septic Shock Using Extracorporeal Device Polymyxin B-Hemoperfusion.
- Resource Type
- Article
- Authors
- Amoruso, Gabriele; Di Venosa, Nicola; Rizzi, Luigi; Lupo, Gianna; Gisotti, Armando; Vitobello, Giuseppe; Mastrandrea, Pasqua; Petta, Rocco; Cinnella, Gilda
- Source
- Blood Purification. 2020, Vol. 49 Issue 5, p627-630. 4p.
- Subject
- *HEMOPERFUSION
*SEPTIC shock
*POLYMYXIN
*SEPSIS
- Language
- ISSN
- 0253-5068
Direct hemoperfusion using polymyxin B-immobilized fiber (PMX-DHP) is an established treatment method for septic shock caused by Gram-negative infections. We report one instance in which PMX-DHP therapy has been used successfully in a 33-year-old woman with septic shock from urosepsis. Although there is lack of recommendations in latest Surviving Sepsis Campaign Guidelines, evidence of PMX-DHP efficacy in this subset of patients is growing. [ABSTRACT FROM AUTHOR]