Implication of CA repeated tracts on post-transcriptional regulation in Trypanosoma cruzi.
- Resource Type
- Article
- Authors
- Pastro, Lucía; Smircich, Pablo; Pérez-Díaz, Leticia; Duhagon, María Ana; Garat, Beatriz
- Source
- Experimental Parasitology. Aug2013, Vol. 134 Issue 4, p511-518. 8p.
- Subject
- *TRYPANOSOMA cruzi
*GENETIC transcription
*GENETIC regulation
*MESSENGER RNA
*SINGLE-stranded DNA
*POLYCARBONATES
*INSECTS
- Language
- ISSN
- 0014-4894
Highlights: [•] CA repeated tracts are present at 3′UTRs of about 10% of T. cruzi genes. [•] Many of them are predicted to exhibit the polyCA in a single stranded conformation. [•] PolyCA insertion significantly increases reporter mRNA level in epimastigote stage. [•] In amastigote stage the reporter mRNA steady state is significantly diminished. [Copyright &y& Elsevier]