Diethyl Phosphite Promoted Electrochemical Oxidation of Tetrahydroisoquinolines to 3,4-Dihydroisoquinolin-1(2 H)-ones.
- Resource Type
- Article
- Authors
- Xie, Wenxia; Gong, Bowen; Ning, Shulin; Liu, Nian; Zhang, Zhuoqi; Che, Xin; Zheng, Lianyou; Xiang, Jinbao
- Source
- Synlett. 2019, Vol. 30 Issue 18, p2077-2080. 4p.
- Subject
- *TETRAHYDROISOQUINOLINES
*OXIDATION
*UNIT cell
- Language
- ISSN
- 0936-5214
A diethyl phosphite mediated electrochemical oxidation strategy for the synthesis of 3,4-dihydroisoquinolin-1(2 H)-ones from tetrahydroisoquinolines under mild conditions has been developed. This protocol provides an environmentally friendly and simple way for the construction of C=O bonds in an undivided cell unit. [ABSTRACT FROM AUTHOR]