Keywords: Allergic rhinitis; cytokines; IL-13; IL-4; siRNA EN Allergic rhinitis cytokines IL-13 IL-4 siRNA 2829 2832 4 09/02/22 20220901 NES 220901 Allergic rhinitis (AR) is a chronic inflammatory disease of upper airways characterized by sneezing, itching, nasal congestion, and rhinorrhea. Anti-inflammatory effect of siRNAs targeted il-4 and il-13 in a mouse model of allergic rhinitis The mouse anti-IL-4 and IL-13 siRNAs3,4 as well as branched (dendrimeric) cationic peptide LTP for nucleic acids delivery into mammalian cells, including lymphocytes (important source of IL-4 and IL-13)5 were designed and tested previously. [Extracted from the article]