Keywords: horse; hypoglycaemia; hypoglycorrhachia; neuroglycopenia; paraneoplasia EN horse hypoglycaemia hypoglycorrhachia neuroglycopenia paraneoplasia 246 249 4 04/06/20 20200501 NES 200501 In light of the fact that maintenance of normoglycaemia is so critical to health, the development of hypoglycaemia is uncommonly encountered in both adult human and equine patients because multiple homoeostatic mechanisms have evolved to prevent or reverse incipient hypoglycaemia. 30 Nauck, M.A., Reinecke, M., Perren, A., Frystyk, J., Berishvili, G., Zwimpfer, C., Figge, A.M., Flyvbjerg, A., Lankisch, P.G., Blum, W.F., Klöppel, G., Schmiegel, W. and Zapf, J. (2007) Hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-I in a patient with metastasizing large-cell carcinoma of the lung. 31 Nirantharakumar, K., Marshall, T., Hodson, J., Narendran, P., Deeks, J., Coleman, J.J. and Ferner, R.E. (2012) Hypoglycemia in non-diabetic in-patients: clinical or criminal? 48 Zapf, J., Futo, E., Peter, M. and Froesch, E.R. (1992) Can "big" insulin-like growth factor II in serum of tumor patients account for the development of extrapancreatic tumor hypoglycemia?. [Extracted from the article]