Under those assumptions, then screening siblings of PA children costs <$100 000/QALY when the prevalence of PA in younger siblings exceeded 11% in the United States or 7.5% in Canada (Figure S2). We modeled one extremely conservative base case scenario in which PA diagnosis was based on skin testing without challenge; although, in a sister analysis, all children with positive skin testing underwent supervised challenge. Identifying infants at high risk of peanut allergy: the Learning Early About Peanut Allergy (LEAP) screening study. [Extracted from the article]