There is ample evidence that fathers and mothers react differently to misbehavior of sons and daughters. Relatively little is known about the mechanisms underlying this differential treatment. This set of quasi-experimental studies examined whether parental attributions about child misbehavior mediate the association between child gender and negative parenting practices, and whether this is different for fathers and mothers. Dutch parents (Study 1: N = 190, 65% mothers, 53% girls; Study 2: N = 287, 56% mothers, 50% girls) of 2- to 4-year-old children were presented with scenarios illustrating child misbehaviors and were asked to imagine their own child in the scenarios. Subsequently, parents were asked about their attributions of the child behavior (Study 1: intentionality, developmental level; Study 2; typicality) and their hypothetical reactions (Studies 1 and 2; negative parenting; Study 2; frustration) in each situation. Study 1 revealed that fathers attributed boys' misbehavior more to being intentional than girls' misbehavior. Fathers' intentional attributions also mediated the association between child gender and negative parenting reactions to child misbehavior. Study 2 revealed that mothers attributed boys' misbehavior more to being typical for the child than girls' misbehavior. For mothers, the association between child gender and negative parenting reactions to child misbehavior was mediated by mothers' typicality attributions and frustration. Thus, gender-differentiated attributions seem to underlie how Dutch fathers and mothers respond to boys' and girls' misbehavior. Yet, both the type of internal attributions and the underlying mechanism for this gender-differentiated attributional process differ for mothers and fathers. Public Significance Statement: This experimental research examined if and why fathers and mothers generally react more negatively to boys' misbehavior compared to girls' misbehavior. It was discovered that the different causes Dutch fathers and mothers attribute to boys' and girls' misbehavior play an important role in this. Fathers attributed boys' misbehavior more to being intentional and mothers attributed boys' misbehavior more to being typical for the child, which in turn predicted more negative parenting reactions to boys' misbehavior. These findings show that it is important to raise awareness in parents of the different causes they attribute to the misbehavior of boys and girls in order to foster more egalitarian parental treatment of boys and girls. [ABSTRACT FROM AUTHOR]