Objective: To investigate primary care practice ownership and specialist‐use patterns for commercially insured children with disabilities. Data Sources and Study Setting: A national commercial claims database and the Health Systems and Provider Database from 2012 to 2016 are the data sources for this study. Study Design: This cross‐sectional, descriptive study examines: (1) the most visited type of pediatric primary care physician and practice (independent or system‐owned); (2) pediatric and non‐pediatric specialist‐use patterns; and (3) how practice ownership relates to specialist‐use patterns. Data Collection/Extraction Methods: This study identifies 133,749 person‐years of commercially insured children with disabilities aged 0–18 years with at least 24 months of continuous insurance coverage by linking a national commercial claims data set with the Health Systems and Provider Database and applying the validated Children with Disabilities Algorithm. Principal Findings: Three‐quarters (75.9%) of children with disabilities received their pediatric primary care in independent practices. Nearly two thirds (59.6%) used at least one specialist with 45.1% using nonpediatric specialists, 28.8% using pediatric ones, and 17.0% using both. Specialist‐use patterns varied by both child age and specialist type. Children with disabilities in independent practices were as likely to see a specialist as those in system‐owned ones: 57.1% (95% confidence interval [95% CI] 56.7%–57.4%) versus 57.3% (95% CI 56.6%–58.0%), respectively (p = 0.635). The percent using two or more types of specialists was 46.1% (95% CI 45.4%–46.7%) in independent practices, comparable to that in systems 47.1% (95% CI 46.2%–48.0%) (p = 0.054). However, the mean number of specialist visits was significantly lower in independent practices than in systems—4.0 (95% CI 3.9%–4.0%) versus 4.4 (95% CI 4.3%–4.6%) respectively—reaching statistical significance with p < 0.0001. Conclusions: Recognizing how privately insured children with disabilities use pediatric primary care from pediatric and nonpediatric primary care specialists through both independent and system‐owned practices is important for improving care quality and value. [ABSTRACT FROM AUTHOR]