Measuring gradients in body fluids – A tool for elucidating physiological processes, diagnosis and treatment of disease.
- Resource Type
- Article
- Authors
- Haslene-Hox, Hanne
- Source
- Clinica Chimica Acta. Feb2019, Vol. 489, p233-241. 9p.
- Subject
- *BODY fluid analysis
*CELL physiology
*EXTRACELLULAR fluid
*CELL compartmentation
*PHARMACOKINETICS
- Language
- ISSN
- 0009-8981
Highlights • The tissue microenvironment has a central role in cell and tissue function. • Substances can be quantified in properly isolated interstitial fluid (IF). • Concentration in IF compared to other fluid compartments inform on substance origin • Drug concentration in IF is important for pharmacokinetic studies and distribution. [ABSTRACT FROM AUTHOR]