Molecular Structure of Escherichia coli PurT-Encoded Glycinamide Ribonucleotide Transformylase.
- Resource Type
- Article
- Authors
- Thoden, James B.; Firestine, Steven
- Source
- Biochemistry. 08/01/2000, Vol. 39 Issue 30, p8791. 12p. 12 Diagrams, 2 Charts.
- Subject
- *MICROBIAL enzymes
*ESCHERICHIA coli
*NUCLEOTIDES
*COMPLEX compounds
*PURINES
- Language
- ISSN
- 0006-2960
Describes the high-resolution x-ray crystallographic structures of PurT transformylase from Escherichia coli. Presence of a form with bound 5'-adenylyl imidodiphosphate and glycinamide ribonucleotide; First ternary complex to be determined for a member of the ATP-grasp superfamily involved in purine biosynthesis.