Reduced brain edema and functional deficits after treatment of diffuse traumatic brain injury by carbamylated erythropoietin derivative.
- Resource Type
- Article
- Authors
- Bouzat, Pierre; Francony, Gilles; Thomas, Sébastien; Valable, Samuel; Mauconduit, Franck; Fevre, Marie-Cécile; Barbier, Emmanuel L.; Bernaudin, Myriam; Lahrech, Hana; Payen, Jean-Francois
- Source
- Critical Care Medicine. Sep2011, Vol. 39 Issue 9, p2099-2105. 7p.
- Subject
- *BRAIN injury treatment
*ERYTHROPOIETIN
*CEREBRAL edema
*HEALTH outcome assessment
*METABOLIC disorder treatment
*EDEMA
*THERAPEUTICS
- Language
- ISSN
- 0090-3493
The article examines the effects of carbamylated erythropoietin on brain edema and functional recovery from diffuse traumatic brain injury. According to the authors, their experiment revealed that early posttraumatic administration of carbamylated erythropoietin helps reduce brain edema development until at least six hours after injury. They also report that early administration improves chances of neurologic recovery. They conclude that carbamylated erythropoietin can be used in reducing edema.