ReDO_DB: the repurposing drugs in oncology database.
- Resource Type
- Article
- Authors
- Pantziarka, Pan; Verbaanderd, Ciska; Sukhatme, Vidula; I., Rica Capistrano; Crispino, Sergio; Gyawali, Bishal; Rooman, Ilse; Van Nuffel, An M. T.; Meheus, Lydie; Sukhatme, Vikas P.; Bouche, Gauthier
- Source
- Ecancermedicalscience. 2018, Vol. 12 Issue 875-886, p1-19. 19p.
- Subject
- *CANCER treatment
*ONCOLOGY
*DRUG abuse
*CLINICAL trials
*DATABASES
- Language
- ISSN
- 1754-6605
Repurposing is a drug development strategy that seeks to use existing medications for new indications. In oncology, there is an increased level of activity looking at the use of non-cancer drugs as possible cancer treatments. The Repurposing Drugs in Oncology (ReDO) project has used a literature-based approach to identify licensed non-cancer drugs with published evidence of anticancer activity. Data from 268 drugs have been included in a database (ReDO_DB) developed by the ReDO project. Summary results are outlined and an assessment of clinical trial activity also described. The database has been made available as an online open-access resource (http://www.redo-project. org/db/). [ABSTRACT FROM AUTHOR]