Keywords: aminoisoquinolinquinones; antimicrobial activity; green synthesis; Piscirickettsia salmonis EN aminoisoquinolinquinones antimicrobial activity green synthesis Piscirickettsia salmonis 85 89 5 12/13/22 20230101 NES 230101 The Chilean and international salmon farming industry is mainly threatened by extensive losses caused by infectious and contagious diseases occurring during the production cycle (Figueroa et al., [10]). Results showed that 25 and 50 g/ml of B 2a b , B 2b b , B 2d b , B 2e b , B 2f b , and B 2 h b compounds reduced cell viability >50% in cells. These results indicate that quinone compounds might represent new alternatives to control infectious diseases. In conclusion, it could be speculated that the bactericidal effect of B 2b b compound is due to the observed cytotoxicity of this compound in CHSE-214 cells. [Extracted from the article]