The Impact of Contrast-Associated Acute Kidney Injury on All-Cause Mortality in Older Patients After Coronary Angiography:A 7.5-year Follow-Up.
- Resource Type
- Article
- Authors
- Guo, Wei; Liu, Jin; He, Yibo; Lei, Li; Guo, Zhaodong; Song, Feier; Zhou, Ziyou; Liu, Wenhai; Zhong, Xian; Chen, Shiqun; Rao, Lifen; Liu, Yong
- Source
- Angiology. May2024, Vol. 75 Issue 5, p434-440. 7p.
- Subject
- *CREATININE
*RESEARCH funding
*ACUTE kidney failure
*CAUSES of death
*DESCRIPTIVE statistics
*MULTIVARIATE analysis
*LONGITUDINAL method
*CORONARY angiography
*CONFIDENCE intervals
*CONTRAST media
*PROPORTIONAL hazards models
*DISEASE risk factors
*OLD age
- Language
- ISSN
- 0003-3197
Older patients (≥75 years) after coronary angiography constitute an increasing proportion, but only limited data are available regarding the prognosis of geriatric contrast-associated acute kidney injury (CA-AKI). Patients (≥75 years) undergoing coronary angiography between December 2010 and September 2013 were consecutively enrolled. CA-AKI was defined as an increase in serum creatinine of 25% or.5 mg/dL from the baseline within 48–72 h of contrast exposure. All-cause mortality was assessed during median 7.5 years (interquartile range [IQR] 6.7–8.7 years) follow-up period. In total, 571 patients aged >75 years undergoing coronary angiography were enrolled in a single center study; 82 (14.4%) patients had CA-AKI. The all-cause mortality during the median 7.5 years follow-up period was 22.0% in patients with CA-AKI and 13.1% in patients without CA-AKI (P =.015). After adjusting for potential confounding factors, the multivariable analysis indicated that CA-AKI was related to an increased risk of all-cause mortality during the median 7.5-year follow-up (hazard ratio [HR]: 2.46; 95% CI: 1.29–4.7; P =.006). CA-AKI is a significant and independent predictor of long-term mortality for patients aged over 75 years who underwent coronary angiography. [ABSTRACT FROM AUTHOR]