Discovery and Preclinical Pharmacology of a Selective ATP-Competitive Akt Inhibitor (GDC-0068) for the Treatment of Human Tumors.
- Resource Type
- Article
- Authors
- Blake, James F.; Xu, Rui; Bencsik, Josef R.; Xiao, Dengming; Kallan, Nicholas C.; Schlachter, Stephen; Mitchell, Ian S.; Spencer, Keith L.; Banka, Anna L.; Wallace, Eli M.; Gloor, Susan L.; Martinson, Matthew; Woessner, Richard D.; Vigers, Guy P.A.; Brandhuber, Barbara J.; Liang, Jun; Safina, Brian S.; Li, Jun; Zhang, Birong; Chabot, Christine
- Source
- Journal of Medicinal Chemistry. 9/27/2012, Vol. 55 Issue 18, p8110-8127. 18p.
- Subject
- *PHARMACOLOGY
*ADENOSINE triphosphate
*PROTEIN kinase B
*PROTEIN kinase C
*BIOMARKERS
- Language
- ISSN
- 0022-2623