ChemInform Abstract: Efficient Iron-Catalyzed Kumada Cross-Coupling Reactions Utilizing Flow Technology under Low Catalyst Loadings.
- Resource Type
- Article
- Authors
- Buono, Frederic G.; Zhang, Yongda; Tan, Zhulin; Brusoe, Andrew; Yang, Bing‐Shiou; Lorenz, Jon C.; Giovannini, Riccardo; Song, Jinhua J.; Yee, Nathan K.; Senanayake, Chris H.
- Source
- ChemInform. Sep2016, Vol. 47 Issue 41, pno-no. 1p.
- Subject
- *IRON catalysts
*CHEMICAL reagents
- Language
- ISSN
- 0931-7597
The first continuous flow iron-catalyzed Kumada cross-coupling is developed for the coupling of 2-chloropyrazine and various aryl Grignard reagents using low catalyst loadings (0.5 mol-%). [ABSTRACT FROM AUTHOR]