Lineage-specific Expansion of KRAB Zinc-finger Transcription Factor Genes: Implications for the Evolution of Vertebrate Regulatory Networks.
- Resource Type
- Article
- Authors
- Hamilton, A. T.; Huntley, S.; Kim, J.; Branscomb, E.; Stubbs, L.
- Source
- Cold Spring Harbor Symposia on Quantitative Biology. 2003, Vol. 68, p131-140. 10p. 6 Diagrams.
- Subject
- *DNA-binding proteins
*TRANSCRIPTION factors
*GENES
*LABORATORY rodents
*VERTEBRATES
- Language
- ISSN
- 0091-7451
Describes a study on Krüppel-associated box-Krüppel-type zinc finger (KK) protein divergence and the evolution of vertebrate regulatory networks. Information on zinc-finger structure and DNA binding; Comparison between KK gene and cluster structure in different rodents; Known regulatory targets of Krüppel-type zinc finger proteins transcription factor proteins.