Kaposi sarcoma (SK) is a conjuctivo-vascular neoplasia with multifocal, systemic character and metastatic capability. The lesions are present in various stages: spot, wound and nodule. The affection is often found in the average-age adult, with an incidence of approximately 2-6 cases in one million individuals. The treatment consists of: radio-chemotherapy, high activity antiretroviral therapy, surgical or laser therapy. The evolution is variable, ranging from several skin lesions to extensive skin forms, but also internal damage. This study presents the case of a 63-year-old male. The patient was hospitalized and treated in the radiotherapy department. The patient presented lesions in the lower limbs. A total dose of 30 Gy was administered, with 3 Gy per fraction, two fractions per week. The device used was GammaMedPlus with Ir192 source. The duration of treatment was five weeks. Five applicators were inserted into the mold and loaded on different lengths (16-23.5 cm). The dose normalization was made at 0.7 cm. After significant wound irradiation, significant local improvements were observed. High-dose rate brachytherapy can be a good option in SK irradiation. [ABSTRACT FROM AUTHOR]