The relationship among the capital lender, the capital borrower and the host country caused from the indirect investment behavior, which referred from the AIIB’s business, is conflict with the ISDS. And the regulation by ICSID, NAFTA and WTO has exposed much of weakness. The investment disputes related to the AIIB should not be submitted to an independent agency whose organization chart and right of competency should be clarified. The loan-investment dispute settlement mechanism should be build and it should achieve new breakthroughs on timeliness in transparency, the appeal system, arbitration and to protect the interests of the developing countries. In the process, the experience for international investment dispute settlement including the TPP should be fully absorbed, for promoting the economic development of countries along the “one belt and one road area”, achieving the AIIB, the borrowed one and the capital importer country tripartite win-win interests.