학술논문

1. ARTICLE

PD-L1P146R is prognostic and a negative predictor of response to immunotherapy in gastric cancer

저자: by Li, Qing ^{1, 2, 9}; Zhou, Zhi-Wei ^{3, 9}; Lu, Jia ³; Luo, Hao ^{1, 7}; Wang, Shu-Nan ⁴; Peng, Yu ⁵; Deng, Meng-Sheng ⁶; Song, Guan-Bin ⁷; Wang, Jian-Min ⁶; Wei, Xi ⁸; Wang, Dong ^{1, ∗}; Westover, Kenneth D. ^{3, ∗∗}; Xu, Cheng-Xiong ^{1, 2, ∗∗∗}
소스: In Molecular Therapy 2 February 2022 30(2):621-631

2. ARTICLE

Loss of wild type KRAS in KRASMUT lung adenocarcinoma is associated with cancer mortality and confers sensitivity to FASN inhibitors

저자: by Liu, Yan ^a; Gao, Galen F. ^b; Minna, John D. ^c; Williams, Noelle S. ^d; Westover, Kenneth D. ^a,
소스: In Lung Cancer March 2021 153:73-80

3. ARTICLE

A highly selective inhibitor of interleukin-1 receptor–associated kinases 1/4 (IRAK-1/4) delineates the distinct signaling roles of IRAK-1/4 and the TAK1 kinase

저자: by Scarneo, Scott A. ^‡; Hughes, Philip F. ^‡; Yang, Kelly W. ^‡; Carlson, David A. ^‡; Gurbani, Deepak ^§; Westover, Kenneth D. ^§; Haystead, Timothy A.J. ^{‡, 1}
소스: In Journal of Biological Chemistry 7 February 2020 295(6):1565-1574

4. ARTICLE

Structural basis of the atypical activation mechanism of KRASV14I

저자: by Bera, Asim K. ^‡; Lu, Jia ^‡; Wales, Thomas E. ^§; Gondi, Sudershan ^‡; Gurbani, Deepak ^‡; Nelson, Andrew ^‡; Engen, John R. ^§; Westover, Kenneth D. ^{‡, 1}
소스: In Journal of Biological Chemistry 20 September 2019 294(38):13964-13972

5. ARTICLE

Intergrated analysis of ELMO1, serves as a link between tumour mutation burden and epithelial-mesenchymal transition in hepatocellular carcinoma

저자: by Peng, Hong ^{a, 1}; Zhang, Yi ^{b, e, 1}; Zhou, Zhiwei ^{c, 1}; Guo, Yu ^{a, 1}; Huang, Xiaohui ^d; Westover, Kenneth D. ^c; Zhang, Zhaohui ^b; Chen, Bin ^b; Hua, Yunpeng ^b; Li, Shaoqiang ^b; Xu, Ruiyun ^e; Lin, Nan ^e; Peng, Baogang ^{b, ⁎}; Shen, Shunli ^{b, ⁎}
소스: In EBioMedicine August 2019 46:105-118

6. ARTICLE

Automated Text Message Reminders Improve Radiation Therapy Compliance

저자: by Tan, Jun ^∗; Christie, Alana ^†; Montalvo, Steven K. ^∗; Wallace, Catherine ^∗; Yan, Yulong ^∗; Folkerts, Michael ^∗; Yingling, Alicia ^∗; Sher, David ^∗; Choy, Hak ^∗; Jiang, Steve ^∗; Westover, Kenneth D. ^{‡, ∗}
소스: In International Journal of Radiation Oncology, Biology, Physics 1 April 2019 103(5):1045-1052

7. ARTICLE

KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS

저자: by Ambrogio, Chiara ^{1, 9, ∗}; Köhler, Jens ^{1, 8}; Zhou, Zhi-Wei ^{2, 8}; Wang, Haiyun ³; Paranal, Raymond ¹; Li, Jiaqi ¹; Capelletti, Marzia ¹; Caffarra, Cristina ¹; Li, Shuai ¹; Lv, Qi ³; Gondi, Sudershan ²; Hunter, John C. ²; Lu, Jia ²; Chiarle, Roberto ^{4, 5}; Santamaría, David ^{6, 9}; Westover, Kenneth D. ^{2, 9, ∗∗}; Jänne, Pasi A. ^{1, 7, 9, 10, ∗∗∗}
소스: In Cell 8 February 2018 172(4):857-868

8. ARTICLE

Studies of TAK1-centered polypharmacology with novel covalent TAK1 inhibitors

저자: by Tan, Li ^{a, b, j}; Gurbani, Deepak ^{c, j}; Weisberg, Ellen L. ^{e, f, j}; Jones, Douglas S. ^{g, h, j}; Rao, Suman ^{a, b, g}; Singer, William D. ^{c, d}; Bernard, Faviola M. ^{c, d}; Mowafy, Samar ^{a, b, i}; Jenney, Annie ^g; Du, Guangyan ^{a, b}; Nonami, Atsushi ^{e, f}; Griffin, James D. ^{e, f}; Lauffenburger, Douglas A. ^h; Westover, Kenneth D. ^{c, d, ⁎}; Sorger, Peter K. ^{g, ⁎}; Gray, Nathanael S. ^{a, b, ⁎}
소스: In Bioorganic & Medicinal Chemistry 15 February 2017 25(4):1320-1328

9. ARTICLE

Structure-guided development of covalent TAK1 inhibitors

저자: by Tan, Li ^{a, b, j}; Gurbani, Deepak ^{c, d, j}; Weisberg, Ellen L. ^{e, f}; Hunter, John C. ^{c, d}; Li, Lianbo ^{c, d}; Jones, Douglas S. ^{g, h}; Ficarro, Scott B. ^{a, b}; Mowafy, Samar ^{a, b, i}; Tam, Chun-Pong ^{a, b}; Rao, Suman ^{a, b, g}; Du, Guangyan ^{a, b}; Griffin, James D. ^{e, f}; Sorger, Peter K. ^g; Marto, Jarrod A. ^{a, b}; Westover, Kenneth D. ^{c, d, ⁎}; Gray, Nathanael S. ^{a, b, ⁎}
소스: In Bioorganic & Medicinal Chemistry 1 February 2017 25(3):838-846

10. ARTICLE

Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine

저자: by Harshbarger, Wayne ^{‡, 1}; Gondi, Sudershan ^{‡, 1}; Ficarro, Scott B. ^{§, 1}; Hunter, John ^‡; Udayakumar, Durga ^‡; Gurbani, Deepak ^‡; Singer, William D. ^‡; Liu, Yan ^‡; Li, Lianbo ^‡; Marto, Jarrod A. ^§; Westover, Kenneth D. ^{‡, 2}
소스: In Journal of Biological Chemistry 6 January 2017 292(1):112-120

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