Probing Cellular Response to Heterogeneous Rigidity at the Micro- and Nanoscale.
- Resource Type
- Theses
- Authors
- Liao, Jinyu
- Source
- Dissertation Abstracts International; Dissertation Abstract International; 78-09B(E).
- Subject
- Biomedical engineering
- Language
- English
Summary: Studies on breast cancer cells indicate that on patterned substrates, sub-cellular processes are also significantly modulated. Integrin recruitment is enhanced on the rigid regions. Understanding the role of geometry in cellular rigidity response will point the way toward revealing its functional response and will shed light on the mechanistic underpinnings of this process.